Wednesday, April 29, 2015

Can taking too many vitamins cause cancer? A study says YES

Vitamins

  Vitamins

Taking Too Many Vitamins May Cause Cancer

BY LIZZY SMITH

In an attempt to heal, stay healthy, and ward of cancer, it may seem tempting to take massive amounts of vitamins. After all, if a few vitamins are good, lots of vitamins must be great, right? If a particular vitamin is a good anti-inflammatory, or if we have low iron levels, or keep getting colds, popping a handful of vitamins seems like a logical idea.

My entire life, I thought that the healthier I was, the greater chance I had of never getting cancer. So I consistently worked out, ate healthy, and took (you guessed it) lots of vitamins. I am not intimating that that’s the reason I got myeloma. Not at all. Why we get this disease I will never know (who does?). But now that I’m on this journey, I do take lots of vitamins in addition to eating loads of organic fresh fruits and veggies, beans, nuts– all the good stuff I can — plus a fair amount of cookies and French fries. See, I’m not perfect. But are those vitamins causing me more harm than good? I’ve run my list of supplements past my doctor. He said not to take large amounts of any supplements and to stay away from curcumin (not every doctor agrees with this approach, so make sure you discuss your situation with your oncologist!). Other than that, no one has told me otherwise. So I’ve been taking some 15 vitamins per day that includes iron, calcium, vitamin-C, vitamin-D, a multi vitamin, fish oil, and more. Good idea? Perhaps not.

Dr. Tim Byers, of the University of Colorado Cancer Center, led research involving thousands of people over a ten-year period. Findings were presented at the American Association for Cancer Research on April 20. Dr. Byers said: “The evidence shows people who take more dietary supplements than needed tend to have a higher risk of developing cancer.” The study further determined that while taking supplements, more people developed more types of cancer.

For example, beta-carotene was found to raise the risk of lung cancer and heart disease by 20 per cent when taken at above the recommended dose.

Vitamin B9, or folic acid, was thought to help reduce colon polyps, which can lead to bowel cancer. But in a trial it actually increased the number of polyps.

For years, I’ve known that vitamins and supplements are never intended to replace a healthy diet. And many vitamins contain far more than a daily recommended allowance, which can lead to a host of problems, including cancer.

But… we myeloma patients are not a typical person. Many of us have real deficiencies and that’s where blood work and a good doctor come in (along with a good nutritionist).

If you don’t know this, here’s a fact: supplements are not regulated like pharma drugs. That means vitamin companies may not be offering top-notch products and their claims may be incredibly misleading. I suppose lesson learned here is to proceed with caution and never take more than the recommended dosage. Eat healthy. Plant-based diets are always a wise idea.

“Taken in recommended amounts, vitamins and minerals are safe,” the study concluded.

For the full article, click here.

Tuesday, April 28, 2015

My life's greatest mission: Finding a cure for myeloma. Upcoming MCRI show to discuss promising clinical trial for high risk patients

Perhaps my life's greatest contribution to humanity (minus raising functioning children) is helping find a cure for multiple myeloma. I am ecstatic to be part of the MCRI (Myeloma Crowd Research Initiative) project. The upcoming radio show is featuring one such potential clinical trial for high risk disease. Tune in, learn more!

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Our Next MCRI Show: Pioneering myeloma immunotherapy with high dose chemo to harness the power of the immune system with Dr. Ivan Borrello, Johns Hopkins, Thursday, April 30 @ 1 pm EST 

Call In by Phone to Listen Live: (347) 637-2631 or Listen Live Via Computer

There are many immunotherapy approaches now being used to target multiple myeloma. One way to use patients’ own immune system to target the myeloma cells is called adaptive T-cell therapy with MILS (marrow infiltrating lymphocytes). Dr. Ivan Borrello is a pioneer to use this therapy (already being used in breast, prostate and pancreatic cancer) in multiple myeloma. He is using the immunotherapy with high dose chemotherapy He will explain how this therapy works and how the resulting promise it shows in early study is now being expanded to a 90 high-risk myeloma patient clinical trial.   

Dr. Ivan Borello, MD is Associate Professor of Oncology, Associate Professor of Cellular and Molecular Medicine for the Graduate Program, and Director of the Cellular Therapeutics Center at the Johns Hopkins School of Medicine. Dr. Borrello’s team of researchers have focused on the development of tumor immunotherapy for blood cancers. This approach is breaking new ground and is a pioneering effort by his team. Dr. Borrello has received numerous awards including the american Society for Clinical Oncology Scholarship Award, the Johns Hopkins University Clinican Scientist Award, the Kimmel Scholar Award, and the Leukemia and Lymphoma Society of America Clinical Translational Scholar Award.

Learn more at www.myelomacrowd.org/mcri or www.myelomacrowd.org

Sunday, April 26, 2015

An interview with my 9-year old daughter: "7 things my mom does that I love"

I love interviewing my daughters, seriously. I always hear something really unexpected. Today I decided to interview my nine-year daughter about what things I do that she loves. I wrote about it on Divorced Moms. If you have children (regardless of their age) or grandchildren, ask them the same question. That'll give you a list of things you should keep doing. On another day when you are really ready for an earful, ask them what things you do that drive them nuts. I'll be asking my 15-year old that question, but not today. Today is just for happy things. Here goes...

My Mom Rocks! 7 Things I Love Best (Says My 9-year Old Daughter)
by Lizzy Smith                    
April 27, 2015
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Fotolia_72225202_XS.jpgI love asking my daughters random questions and then listening to what they say. I often learn so much from them. While I know that I'm driving my teen daughter a little nutty lately, I also know I get some things right. Since today I wanted to focus only on the positive, I decided to ask my nine-year old daughter what things I do that she loves. Before she answered, I vowed that whatever she said, I'd do my best to continue doing it. On another day, I'll ask her what I do that I should try and stop. But that's for another time. Here are her answers:

1. You let me cook with you
I love to experience cooking and to learn to cook new things. It's really fun to spend time with my mom doing this together. I also love to eat what we cook with the whole family. I like to invite a lot of people over so they can eat with us. I love when we all eat together and get to talk.

2. I love when you drive carpool
When my mom drives, I don't have to walk as far because she drops us off right in front of the school. When my mom picks us up sometimes we get to go out and get ice cream. Sometimes my mom takes all the kids in the carpool to get cookies. The kids think my mom is awesome when she does that.

3. My mom takes me to my favorite restaurant
I love Tepenyaki and it is really expensive. We go every year on my birthday. It is really fun to watch the guy cooking our food and trying to throw shrimp for us to catch in our mouths. I love when my mom lets me pick going to my favorite restaurant. Tepenyaki is really funny and my sister, my mom and I laugh a lot at dinner.

4. Shopping together is really fun
I love shopping with my mom. Going out with just us girls is really fun. Sometimes my mom lets me pick out craft projects or I get to try on cute clothes. I love feeling fashionable with my mom and she can be really funny when we are picking out things. She tells me a lot that a girl can never have too many shoes.

5. I love going on trips with my mom
I love going to fun places with my mom and sister. She takes us really fun places. I love going on cruises the best because there is kids club. We also get to go places that I see in pictures and TV. When we talk about places at school I have been to a lot of them and I like to tell the teacher about it. I went to where Abraham Lincoln was shot and then where he died. I loved snorkeling in Honduras. But my favorite place was Dubrovnik, Croatia where we walked along a long city wall and took a lot of funny pictures. Like I climbed on a cannon and make crazy faces. It was really beautiful and fun and we could see the ocean from the top of the walls. The stairs were really hard and steep to climb. My mom, sister and I have a lot of fun when we go places together. My mom likes to take us places together and she is really funny when we are away from our house.

Keep reading...

Friday, April 24, 2015

Myeloma and alternative therapies. My trial of cannibidiol (CBD)


I have been battling multiple myeloma since diagnosis in January 2012. When I first started treatment, I thought about going completely alternative. That means foregoing toxic drugs and chemotherapy and going all natural. Make radical changes to my diet, take vitamins, and pick one of the anti-cancer protocols.

But then I wasn't brave enough to do that. Maybe the cure for cancer is in plants. But I just couldn't do it. I did, however, decide that I would do all I could to give my body all the fighting power it needed and then do all that chemo and transplants and chemicals.

Over the course of my myeloma journey, I have started hearing about the effectiveness of cannibidiol (CBD). In fact, my fellow myeloma survivor and advocate, Gary Petersen, wrote about it on his blog:
This Cure Panel broadcast was aired on April 15 and you can listen to the rebroadcast if you CLICK HERE.  I had been knowledgeable of the fact cannabis was proven to be able to mitigate the nausea and discomfort caused by many therapeutic chemotherapy drugs.  However, what has recently been discovered is that cannibidiol (CBD), a non-psychoactive component of marijuana, had therapeutic value in multiple myeloma treatment.  After studying the effects of cannabidiol on multiple myeloma cells, researchers found that, “CBD by itself or in synergy with Bortezomib strongly inhibited growth, arrested cell cycle progression and induced MM cells death by regulating the ERK, AKT and NF-κB pathways with major effects in TRPV2+ cells.” They conclude that, “These data provide a rationale for using CBD to increase the activity of proteasome inhibitors in MM.”  Cannabis and Cialis, if it doesn't cure your myeloma you may just go out with a big SMILE on your face.  
I am pro medical marijuana and using hemp but it's not legal here in Utah. I don't really understand how to use it or why. Or if it'll negatively interact with the drugs that I take now (namely Revlimid, Carfilzomib, and Dex). But I would be willing to try it.

About a year ago, I was chatting up with my fellow myeloma warrior, Jenny, about if I should take curcumin supplements. My doctors at Huntsman said no, it could diminish the effectiveness of chemo. Other myeloma doctors say yes. Jenny said at one point you need to study and pray and just decide what's best for you. I decided to take the supplements. So before I go further, know that I am not telling other myeloma patients that they should do what I'm doing. I can only tell you what I've decided, my experience, and then talk to your doctor, nutritionist, God or higher power, and then make your own (informed) decisions.

So what is cannibidiol? Let's here from Dose of Nature, a company that makes it:

Cannabinoids (cannabidiol/CBD) are natural constituents of the hemp plant and CBD is derived from commercial hemp stalk and seed.
The United States Food and Drug Administration (FDA) currently considers non-THC hemp based cannabinoids, including CBD, to be “food based” and therefore sale-able. These new non-psychoactive CBD-rich hemp oil products that ETST has geared up to market and distribute are beyond reproach. CBD (cannabidiol), a naturally occurring constituent of the industrial hemp plant, promotes and supports the nutritional health of aging bodies in particular. Source: US Government Patent #6,630,507 “Cannabinoids as antioxidants and neuroprotectants.”
While the standard of the industry has been a CO2 extracted paste and that same paste mixed with oils, Dose of Nature has pushed the envelope forward in terms of better delivery options, bioavailability and taste. Dose of Nature launched with a three-tiered CBD (cannabidiol) product line:
RedStrap™ CBD oil blends:
What makes their product line unique is because they use the purest, most refined CBD oil available in the world. Dose of Nature’s proprietary process takes out the unnecessary waxes, resins, and constituents, rendering a cleaner natural supplement.
CBD glycerin tincture:
Dose of Nature’s Sweet CBD™ is the only glycerin CBD product available at the national level. Dose of Nature’s proprietary BioXTrax™ process extracts whole herbs and nutrients through an elaborate multi-stage process binding them into a concentrated glycerin solution which is sweet, water-soluble, and easily digested and bioavailable.
Nano-Technology: The Dose of Nature Hydrosome™ technology creates uniform, true nano-sized particles that are embedded in micro-water clusters for easy absorption at the cellular level.

About a month ago, I went for it-- I tried cannibidiol (CBD) from Dose of Nature. I loved it and plan to continue taking it. I don't have new markers drawn and I can't tell you that clinically anything has changed. But I can give you my experience and some info...

It was easy to take and I immediately noticed an increase in energy when taking it in the mornings. Since fatigue is a real side effect of many myeloma meds, especially on the days I'm crashing from Dex, this was a Godsend. Also, I struggle with chemo brain. On cannibidiol, I noticed that I had greater mental clarity and more easily remembered things. I also had less pain in my joints. Sometimes my entire torso aches and despite successful stem cell transplants, the pain never seems to go away entirely. Some days are worse than others. I also get leg cramps at night. When taking the oil, I experienced no leg cramps at all. Yay!

Am I going to continue taking it? Yes. If you're interested in more information, visit www.doseofnature.com. The price for the Dose of Nature Redstrap CBD is $79.99. I used it by putting it in my morning fruit smoothy of an orange, banana, frozen pineapple, chia seeds, and unsweetened organic coconut milk. Yum!

Divorced Moms: Becoming Bully-Proof During The Divorce Process. 5 Survival Tips

I know too many people going through a divorce these days. And it is amazing how many of the women out there are willing to give in to their ex just to get it over with. They are bullied, afraid, coerced, manipulated into agreeing to things that are to their own detriment. Why is that? Because they aren't strong. Now is NOT the time to be weak. Now is the time to find your inner WARRIOR and fight for YOU. I was nearly that woman, ready to give in to my ex. He felt my weakness. I was, after all, sick and fighting cancer. The horrific things he said were unbelievable. I nearly gave him everything just to make it stop. Until I didn't. Refusing to be bullied was an amazing moment. When I took my sanity back. If you're in the divorce process, or even considering a divorce, NOW is the time to get STRONG. Research. Know your rights. Stay calm.

Enjoy the article.

Becoming Bully-Proof During The Divorce Process. 5 Survival Tips
by Lizzy Smith                    
April 24, 2015
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I have two friends who are at opposite ends of the divorce spectrum.

Kristen
"Kristen" and "Chad" have been married for 28 years and have four children together. Kristen is a stay at home mom and hasn't worked a day in her life. While Kristen acknowledges that her marriage had gotten boring for the past many years, there was never a hint of real trouble or unhappiness. Chad never once mentioned a separation or divorce until he came home one day and told her he just bought a home, he was moving out, and their marriage was over. Kristen was completely blindsided. Three weeks later, Chad moved out, handed her a divorce settlement, and said that she had 24-hours to agree to it and if she didn't, she would get a lot less with attorneys involved.

I begged her to not sign, get an aggressive attorney, and let the process play itself out. Kristen didn't want to fight. Maybe he'll reconsider. Even if he doesn't, he has her and their children's best interests at heart and would never try to screw them over. She wants to just sign the papers. She feels broken, afraid, and already tired.

Shari
"Shari" and "Ronald" have been married for ten years and Shari has wanted out of the marriage for several years. She has mentioned divorce to Ronald but somehow, they are both still hanging on, hoping that they will be able to fix the relationship. Always the planner, Shari is taking nothing for granted, however. She has already interviewed several attorneys "just in case." She knows what steps she must take if separation becomes a necessity. She wants to stay living in their home while the divorce moves forward and if Ronald refuses to move out, she knows exactly what steps she must take to request a move from a judge. If that fails, Shari has already scoped out rentals. She has made a budget to ensure she can afford life without Ronald, and she is as mentally and emotionally prepared as she can be.

Me
...And then there's me. Like Shari, I wanted a divorce from my husband from just months into our marriage. When I finally discovered that his bizarrely explosive and unpredictable behavior stemmed to alcoholism (I was totally unaware of his addiction while we were dating, call me stupid), I knew that our marriage was on borrowed time. Over the course of our marriage, I interviewed attorneys, maintained a good job, and knew exactly where I was moving when I finally pulled the plug. When I finally left my husband, it was chaos and something I could not have predicted. I was diagnosed with cancer and just days later, packed things into trash bags and moved two states away and into my parents' basement. I then hired an attorney and started fighting the husband and cancer at the same time.

While divorce and splits are never pretty or perfect, being mentally and emotionally prepared is essential. In my case, I ended up hiring my husband's ex-wife's attorney. I had interviewed her before and I liked her. I knew from first-hand experience that she was aggressive and knew her stuff. When my husband battled his ex-wife, she won every single time and Rob (my husband) was terrified of her. When Rob tried to bully me during the divorce and get me to sign and agree to things that were to my detriment, I cut off all contact with him. It took almost two years to finalize our divorce and I was prepared for the long battle.

Divorce can take a long time. Know that. Take a deep breath. Go to yoga if you must. Be calm. And then let the process play itself out. If your ex is trying to speed it up, or never stops screaming at you, or is promising that the two of you might get back together if you'll just be reasonable and sign your rights away, STOP. Do NOT listen to him.

Whether you are in the divorce process, are considering it, or perhaps are just feeling in your gut that things aren't ok in your marriage, getting prepared is in your best interest. Here are 5 ways you can do just that:

1. Interview attorneys

Keep reading...

Tuesday, April 21, 2015

Who did a BOUDOIR photo shoot? That would be ME! Sharing the tale is BRAVE, if you ask me

This was one very fun experience! Writing about it? Fun. Brave. Very raw. Here goes! My latest via Divorced Moms. Yes, even cancer survivors can feel (and be) sexy.

Finding Sexy At 47. My Boudoir Photography Shoot
by Lizzy Smith                     
April 21, 2015
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wardrobe.jpgLife has physically beaten my body up and it shows. New wrinkles, sagging skin, bags around my eyes.

First: I am 47 years old. It is really strange, I have to say, to sometimes look in the mirror and I hardly recognize myself. My eyes look different. More hollow. Bags. Wrinkles in my forehead. Lips nearly disappearing. I look at my legs. Sagging skin that seem to fall off bones. It's that natural aging process.
I used to fear getting old, though since getting cancer, I embrace it. Please, God, let me grow old, really old. But it's still hard looking in the mirror and seeing change.

Second: For the past three years and four months, I've been battling cancer (multiple myeloma, a blood cancer, the same disease that Tom Brokaw has). Since diagnosis, I have had two stem cell transplants, massive amounts of toxic drugs including chemo, lost all my hair, eyelashes and eyebrows, and have had non-stop maintenance therapy of more toxic drugs. One of the medications I take, Dexamethasone (a steroid) can be blamed for muscle loss, fat tissue in my face, weight gain, and loads of insomnia. On the days I take it (typically on Mondays), it turns my normal sweet disposition (haha) into an amped up monster. My children know to be very careful around Mom during Dex days.

Third: I suffered a horrific marriage to a (highly functioning) alcoholic who was extremely verbally and emotionally abusive. Upon cancer diagnosis, I finally left him. But the abuse was about to begin in earnest once that happened. He started off with threatening me that if I didn't return home, he would cancel my health insurance. When that failed to work, he tried to bully and coerce me into signing a divorce decree that was in his best interest and to my detriment. While telling everyone, including the courts, that I was faking cancer to get sympathy and that I was lazy and needed to get my ass back to work, he also thought that I was weak and it was a perfect time to (figuratively) kick me in the head. He thought wrong. His threats helped me to get into fighting mode. I was going to kick him and cancer in the ass at the same time. I did, it worked.

But all of these stressors have made me feel most unsexy and desirable. While these days I'm healing, in love again, engaged, and actively involved in causes I love (namely the cancer and divorce communities) and I live my life to the fullest- traveling and experiencing life, I don't feel, well, sexy. And I want to. Certainly in my aging, health-failing body, there is something to celebrate and embrace in this very un-perfect body.

I did get Botox. It helped. I love it and I have no regrets. I'm open about it, too. I get those icky shots in my forehead. It helps my eyes look less hollow. I got lip fillers because those tiny, thin old lady lips were just not working for me. It's very subtle and I love it. Maybe I'll even get fillers somewhere in my face some day. But I don't want to look overly-done. So one thing at a time.

I did re-do my wardrobe almost entirely since my cancer diagnosis. Pitched pretty much all the old. I dress with more color, more whimsical and a little bohemian at times. Something radically different that when I was married and I tended to dress more conservative, more Ann Taylor. These days I wear a bright apple green Kate Spade handbag. With warmer temps, I'm back in bling-y sandals. My hair color went from brunette to blonde. My favorite stores are Free People and Anthroplogie.
But to really celebrate sexy, I needed to pick it up a HUGE notch.

Just before diagnosis, I was at work and my colleague confessed that she was doing a boudoir photography shoot. "I've always wanted to do it," she said. "I'm going to have a few glasses of wine and get semi-nude." It sounded so bold, brave and fun. I vowed then that someday I would do it, too. That time was now.

I found Victoria Lynn Photography (www.hollywood-fx.com or 801-688-1263) in Salt Lake City, Utah and gave her a call. She sounded so warm, fun and easy to work with. She told me she had loads of costumes, shoes, and jewelry if I didn't have my own. She could even do my hair and makeup. I opted for the makeup but brought my own clothes (a taffeta skirt from White House Black Market) and gold sparkly shoes that I am obsessed with. I did borrow a hat and necklace, though.

Keep reading...

Sunday, April 19, 2015

Next MCRI Radio Show is TOMORROW! Join me in learning more about how we can cure myeloma

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Our Next MCRI Show: Uncovering Clues and Cures for High-Risk Myeloma using Flow Cytometry Testing with Dr. Bruno Paiva, PhD, University of Navarra, Monday, April 20 @ 11 am CST     

Monday, April 20, 9:00 am PST, 10:00 am MST, 11:00 am CST, Noon EST

Call In by Phone to Listen Live: (347) 637-2631 or Listen Live Via Computer

Today, the myeloma community waits 2-3 years to determine if new drugs will work for high-risk myeloma patients through a lengthy trial and error process. Dr. Paiva’s goal is to use more sensitive flow cytometry tests to cut that time short and identify working therapies more rapidly. Using the older flow cytometry tests, the percentage of patients who achieve a deep minimal residual disease (MRD) response is the same for standard or high-risk patients. Additionally, the percentage of chemoresistant MRD cells is similar in both groups. With a background in the evolution of myeloma, his research aims to ask the question if using next-generation, more sensitive flow cytometry tests could identify how patients will respond to new drugs and how new treatments would impact patients with high-risk features. The new flow cytometry tests are now looking at the actual biology of the residual cells, providing clues into the discovery of cures, especially for high-risk patients. The new method is relatively fast, highly sensitive and can detect ultra low levels of MRD. 

Dr. Paiva, PhD is Scientific Coordinator of the Flow Cytometry Department and CIMA Lab Diagnostics group at the University of Navarra in Spain. He teaches courses regularly on cellular biology, techniques of quantification and analysis, new treatments in hematological cancers, inflammation as it relates to the blood and minimal residual disease. His work and that of the Spanish group has performed extensive research appreciated by the world of myeloma practitioners on the flow cytometry test as it relates to minimal residual disease. Dr. Paiva specializes in understanding the heterogeneity (or biological complexity) of MGUS, smoldering myeloma, active multiple myeloma and how it evolves. He is involved in both the detection and classification of myeloma and has written numerous papers on the topic, writing or speaking on the subject over 140 times. Dr. Paiva has also been Principal Investigator on clinical trials utilizing immunotherapies including the SAR650984 anti-CD38 monoclonal antibody. He participates as ad-hoc reviewer for Blood Cancer Journal, Blood, Pathobiology, Leukemia and several other publications. He received a premier ASH Abstract award in 2014, 2013, 2012 and Young Investigator Award by the IMF to name just a few.